Cell BiologybioRxiv
Gene editing can generate fragile bivalents in mouse oocytes
M. Manil-Segalen, M. Łuksza, J. Kannaan…·M.-H. Verlhac
This study shows that excessive microtubule nucleation from fragmented acentriolar MTOCs in mouse oocytes leads to chromosome breakage during meiosis.
DOI 10.1083/jcb.201806072