Cell BiologybioRxiv
Dose-dependent effects of histone methyltransferase NSD2 on site-specific double-strand break repair
K. IWASAKI, H. KOBAYASHI, Y. Kamimura…·K. URA
This study shows NSD2 has dose-dependent effects on DSB repair pathways, repressing non-c-NHEJ and promoting c-NHEJ while not affecting HR or total NHEJ efficiency.