Cell BiologybioRxiv
Endothelial-immune crosstalk contributes to vasculopathy in non-alcoholic fatty liver disease
C.-Y. Ng, K. L. Lee, M. D. Muthiah…·C. Cheung
This study investigates endothelial-immune interactions in NAFLD, showing increased chemokine expression and immune cell infiltration, and demonstrates that targeting the CXCL12-CXCR4 axis can restore endothelial barrier function.