BiochemistrybioRxivPreprint
Drug-bound and -free outward-facing structures of a multidrug ABC exporter point to a swing mechanism
v. Chaptal, V. Zampieri, B. Wiseman…·P. G. Falson
The paper resolves two ATP-Mg2+-bound outward-facing conformations of BmrA, revealing a swing mechanism for drug transport through structural and dynamic analyses.
DOI 10.1101/2021.03.12.435132