Molecular BiologybioRxivPreprint
Mapping host-microbe transcriptional interactions by dual perturb-seq
Simon W Butterworth, Kristina Kordova, Sambamurthy Chandrasekaran…·Moritz Treeck
This paper introduces dual perturb-seq, a method combining CRISPR screening and single-cell RNA-sequencing to identify host-microbe transcriptional interactions, revealing new effector proteins in Toxoplasma gondii.