Pharmacology & ToxicologyBritish Journal of PharmacologyPeer-reviewed
Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target
Yugesh Kharel, Tao Huang, Kyle Dunnavant…·Kevin R. Lynch
This study evaluates a novel S1P transport blocker, SLF80821178, showing efficacy in multiple sclerosis without the cardiac side effects of SRMs, but with less lymphopenia and unchanged lymph S1P levels.
4 citations