Caitlin M. Pavelec

This study identifies mTOR as a therapeutic target for MYBPC3 mutation-induced hypertrophic cardiomyopathy using network modeling and experimental validation.

The paper shows nitrosation of CD36 by nitric oxide prevents endothelial lipid uptake and maintains function in obesity.

This study evaluates a novel S1P transport blocker, SLF80821178, showing efficacy in multiple sclerosis without the cardiac side effects of SRMs, but with less lymphopenia and unchanged lymph S1P levels.

This study shows Sarm1 promotes the transition from protective to repair Schwann cell states after nerve injury, with implications for neuropathies and neurodegenerative diseases.

This study shows that PANX1 deficiency in cardiomyocytes reduces glycolytic metabolism and protects against cardiac hypertrophy in non-ischemic heart failure by decreasing neutrophil recruitment.