Author

Katherine Y. Zhong

Vanderbilt University

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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Ann Thomas TateiD· 1 shared Arun PrakashiD· 1 shared Justin T. CritchlowiD· 1 shared

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Ann Thomas TateORCID

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Evolutionary BiologyPLoS PathogensPeer-reviewedFeb 26, 2024

Mapping the functional form of the trade-off between infection resistance and reproductive fitness under dysregulated immune signaling

Justin T. Critchlow, Arun Prakash, Katherine Y. Zhong, Ann Thomas Tate

This study quantifies the trade-off between immune investment and host fitness by manipulating cactus knock-down in flour beetles, revealing dose-dependent benefits and costs to infection resistance and other fitness traits.

32 citationstop 4%

Drosophilaexperimental assay

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