Author

Katja R. MacCharles

Simon Fraser University

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1

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Esther M. VerheyeniD· 1 shared Gamze Akarsu· 1 shared Joy Marion RichmaniD· 1 shared Kenneth Kin Lam WongiD· 1 shared

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2024-2024 · peak 1/yr

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Esther M. VerheyenORCID

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Developmental BiologybioRxivPreprintSep 10, 2024

Robinow Syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong…·Esther M. Verheyen

This study investigates the effects of a DVL1 variant in a Drosophila model of Robinow Syndrome, showing disrupted morphogenesis and appendage formation with increased cell death and basement membrane changes.

1 citation

Drosophilaexperimental assay

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