ImmunologybioRxivPreprint
DNAM-1 immunoreceptor integrates innate and adaptive immune programs to drive intestinal inflammation
Natsuki Ide, kazuki Sato, Kyoko Oh‐oka…·Akira Shibuya
This study identifies DNAM-1 as a key integrator of innate and adaptive immune responses in intestinal inflammation, showing it drives colitis through distinct mechanisms in ILC3s and dendritic cells and highlights its potential as a therapeutic target.