NeurosciencebioRxivPreprint
SYNGAP1 deficiency disrupts neoteny in human cortical neurons in vivo.
Ben Vermaercke, Ryohei Iwata, Keimpe Weirda…·Pierre Vanderhaeghen
This study shows that SYNGAP1 deficiency causes accelerated synaptic development and disrupted neoteny in human cortical neurons transplanted into mice, linking it to ID/ASD.