NeuroscienceJournal of Biological ChemistryPeer-reviewed
N-Glycosylation is a Potent Regulator of Prion Protein Neurotoxicity
Kevin M. Schilling, Pooja Jorwal, Natalia C. Ubilla‐Rodriguez…·Glenn L. Millhauser
This study shows that N-linked glycans on PrPC are essential for maintaining a non-toxic structure and suppressing neurotoxicity through intramolecular interactions.
15 citations