Author

Kotone Ishii

Tohoku University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Hiroyuki KumetaiD· 2 shared Masaki OkumuraiD· 2 shared Motonori MatsusakiiD· 2 shared Shingo KanemuraiD· 2 shared Tomohide SaioiD· 2 shared Airu Takeuchi· 1 shared Eiichiro MoriiD· 1 shared Hiroya AbeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Hiroyuki KumetaORCID

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2 papers

Recent·Most cited

BiochemistryNature Cell BiologyPeer-reviewedNov 1, 2025

Ca2+-driven PDIA6 phase separation to ensure proinsulin quality control

Young‐Ho Lee, Tomohide Saio, Mai Watabe…·Masaki Okumura

This study shows Ca2+ induces PDIA6 phase separation, enhancing proinsulin folding and preventing aggregation through recruitment of PDIA3.

16 citationstop 3%

protein structureexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintMar 4, 2024

Client recognition differences between PDI and ERp46 to guide oxidative folding

Tomohide Saio, Kotone Ishii, Motonori Matsusaki…·Masaki Okumura

The paper compares how PDI and ERp46 recognize client proteins during oxidative folding, showing distinct mechanisms that influence disulfide bond formation and protein quality control.

5 citations

protein structureexperimental assay

𝕏 PostBluesky