Author
University of Vermont
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Kristin C. Schutz, Olivia Evans, Jacob R. Mackinder…·Matthew J. Wargo
This study identifies genes affecting PlcH production in Pseudomonas aeruginosa using a genome-wide transposon screen and confirms their roles through deletion mutants.
Pauline A DiGianivittorio, Kristin C. Schutz, Lauren A. Hinkel, Matthew J. Wargo
This paper shows that PlcH and C. perfringens alpha toxin hydrolyze sphingosylphosphorylcholine (SPC), a signaling sphingolipid, which may be a common target for phosphocholine-specific phospholipases during infection.
Pauline DiGianivittorio, Lauren A. Hinkel, Jacob R. Mackinder…·Matthew J. Wargo
This study shows that Pseudomonas aeruginosa uses the sphBC genes to metabolize sphingosine, reducing its inhibitory effects on bacterial growth.
Jacob R. Mackinder, Lauren A. Hinkel, Kristin C. Schutz…·Matthew J. Wargo
This paper shows that sphingosine induces PlcH transcription in Pseudomonas aeruginosa via SphR, through a promoter upstream of cerN and read-through of its terminator.