Eric A. Klein

Pharmacologically inhibiting beta-adrenergic receptors during chronic stress mitigates reductions in anaerobic, short-chain fatty acid-producing bacteria in the gut.

This study identifies anionic bacterial sphingolipids, specifically ceramide phosphoglycerate, and shows they increase membrane zeta potential and stiffness.

This study presents five high-resolution structures of CpgD, revealing van der Waals interactions mediate its enantiomeric substrate preference for 2-phospho-D-glycerate.

This study identifies sphingolipid transport proteins in Caulobacter crescentus that function similarly to LPS transport proteins, revealing a shared transport mechanism.

The paper identifies CpgD as a phosphoglycerate cytidylyltransferase essential for ceramide diphosphoglycerate synthesis in Caulobacter crescentus.

This study shows that Pseudomonas aeruginosa uses the sphBC genes to metabolize sphingosine, reducing its inhibitory effects on bacterial growth.

The paper investigates the subcellular localization of bacterial sphingolipid synthesis enzymes to determine the order of reactions in the pathway.