NeuroscienceCell ResearchPeer-reviewed
PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins
Yongjia Duan, Aiying Du, Jinge Gu…·Yanshan Fang
This study shows PARylation regulates RNP granule dynamics and neurotoxicity of disease-related RNA-binding proteins, with PARP inhibition reducing neurotoxicity in ALS models.
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