Author

Kyle C. Dent

MRC Laboratory of Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam M. DinaniD· 1 shared Alan John WarreniD· 1 shared Aldema Sas‐CheniD· 1 shared Alexander J. WhitworthiD· 1 shared Andrew E. FirthiD· 1 shared Byron AndrewsiD· 1 shared Caterina GaroneiD· 1 shared Christopher J. RussoiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Adam M. DinanORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedFeb 17, 2022

A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit

Pedro Rebelo‐Guiomar, Simone Pellegrino, Kyle C. Dent…·Michal A. Minczuk

This study identifies a late-stage quality control step in human mitochondrial ribosome large subunit assembly, showing that MRM2 ablation impairs oxidative phosphorylation through defective translation and accumulation of assembly intermediates.

47 citations

humanmetagenomics

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Molecular BiologybioRxivPreprintOct 21, 2020

Structural basis for the inhibition of the SARS-CoV-2 RNA-dependent RNA polymerase by favipiravir-RTP

Katerina Naydenova, Kyle Muir, Long-Fei Wu…·Christopher J. Russo

This study determines the structure of favipiravir-RTP bound to SARS-CoV-2 RdRp, revealing its weak incorporation mechanism and low replication suppression.

2 citations

experimental assay

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