Cell BiologybioRxiv
Macrophages provide a transient muscle stem cell niche via NAMPT secretion
D. Ratnayake, P. D. Nguyen, F. J. Rossello…·P. D. Currie
The paper identifies macrophages as a transient niche for muscle stem cells through NAMPT secretion, which activates CCR5 on stem cells to drive muscle regeneration.
DOI 10.1038/s41586-021-03199-7