Cancer BiologybioRxiv
Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers
D. H. Peng, B. L. Rodriguez, L. Diao…·D. L. Gibbons
This study shows that Th17 cells contribute to resistance to MEK inhibitor and anti-PD-L1 therapy in KRAS/p53 mutant lung cancers and suggests a triple combinatorial therapy to overcome resistance.
DOI 10.1038/s41467-021-22875-w