Author

L. A. Lofgren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

B. S. Ross· 3 shared J. E. Stajich· 3 shared R. A. Cramer· 3 shared C. H. Kowalski· 2 shared J. J. Obar· 2 shared A. Ashare· 1 shared A. K. Caffrey-Carr· 1 shared D. L. Mould· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

B. S. Ross

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Decoding the chemical language of Suillus fungi: genome mining and untargeted metabolomics uncover terpene chemical diversity

S. Mudbhari, L. A. Lofgren, M. R. Appidi, R. Vilgalys, R. L. Hettich, P. E. Abraham

This study combines genomics and metabolomics to identify terpene diversity in Suillus fungi, revealing metabolites involved in fungal communication and host interactions.

bioRxiv · Nov 20, 2023 · PreprintMicrobiology

Host lung environment limits Aspergillus fumigatus germination through a SskA-dependent signaling response

M. E. Kirkland, M. Stannard, C. H. Kowalski, D. L. Mould, A. K. Caffrey-Carr, R. M. Temple, B. S. Ross, L. A. Lofgren, J. E. Stajich, R. A. Cramer, J. J. Obar

The paper identifies a SskA-dependent signaling pathway that limits Aspergillus fumigatus germination in the host lung environment, enhancing disease initiation and inflammation.

bioRxiv · Aug 27, 2021Microbiology

Aspergillus fumigatus In-Host HOG pathway mutation for Cystic Fibrosis Lung Microenvironment Persistence

B. S. Ross, L. A. Lofgren, A. Ashare, J. E. Stajich, R. A. Cramer

This paper identifies a unique Pbs2 MAPKK allele in Aspergillus fumigatus isolates from CF patients that enables lung persistence by enhancing osmotic stress response in low oxygen but reducing oxidative stress resistance in standard conditions.

bioRxiv · Feb 17, 2021Microbiology

Strain specific persistence in the murine lung of Aspergillus fumigatus conidia causes an Allergic Broncho-Pulmonary Aspergillosis-like disease phenotype

J. T. Jones, K.-W. Liu, X. Wang, C. H. Kowalski, B. S. Ross, K. A. M. Mills, J. D. Kerkaert, T. M. Hohl, L. A. Lofgren, J. E. Stajich, J. J. Obar, R. A. Cramer

This study identifies an A. fumigatus strain, W72310, that persists in the mouse lung and causes ABPA-like disease without significant hyphal growth.

bioRxiv · Dec 4, 2020Microbiology

Does fungal competitive ability explain host specificity or rarity in ectomycorrhizal symbioses?

P. Kennedy, J. Gagne, E. Perez-Pazos, L. A. Lofgren, N. H. Nguyen

This study investigates whether competitive ability explains host specificity or rarity in ectomycorrhizal fungi, finding that S. subaureus is not a poor competitor but has delayed colonization.

bioRxiv · May 20, 2020Ecology