Author

R. L. Hettich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 8 Ecology· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:metagenomics· 8 Research Focus:cell type annotation· 7 Approach:experimental assay· 7 Assay:proteomics· 4 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

P. E. Abraham· 3 shared S. L. Peters· 3 shared F. E. Löffler· 2 shared J. F. Banfield· 2 shared M. J. Morowitz· 2 shared M. R. Olm· 2 shared R. Baker· 2 shared R. Bernier-Latmani· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

P. E. Abraham

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Decoding the chemical language of Suillus fungi: genome mining and untargeted metabolomics uncover terpene chemical diversity

S. Mudbhari, L. A. Lofgren, M. R. Appidi, R. Vilgalys, R. L. Hettich, P. E. Abraham

This study combines genomics and metabolomics to identify terpene diversity in Suillus fungi, revealing metabolites involved in fungal communication and host interactions.

bioRxiv · Nov 20, 2023 · PreprintMicrobiology

Functional analysis of Salix purpurea genes support roles for ARR17 and GATA15 as master regulators of sex determination

B. Hyden, D. L. Carper, P. E. Abraham, G. Yuan, T. Yao, L. Baumgart, Y. Zhang, C. Chen, R. O'Malley, J.-G. Chen, X. Yang, R. L. Hettich, G. A. Tuskan, L. B. Smart

This study functionally characterizes candidate sex determination genes in Salix purpurea using Arabidopsis, supporting ARR17 and GATA15 as master regulators and identifying downstream transcription factors.

bioRxiv · Apr 21, 2023 · PreprintPlant Biology

Meta-omics-aided isolation of an elusive anaerobic arsenic-methylating soil bacterium

K. Viacava, J. Qiao, A. Janowczyk, S. Poudel, N. Jacquemin, K. L. Meibom, H. K. Shrestha, M. C. Reid, R. L. Hettich, R. Bernier-Latmani

The paper isolates an anaerobic arsenic-methylating bacterium using meta-omics approaches to overcome challenges in functional isolate identification.

bioRxiv · Jan 25, 2022Microbiology

Active anaerobic methane oxidation and sulfur disproportionation in the deep terrestrial subsurface

E. Bell, T. Lamminmaki, J. Alneberg, C. Qian, W. Xiong, R. L. Hettich, M. Frutschi, R. Bernier-Latmani

The paper demonstrates active anaerobic methane oxidation and sulfur disproportionation in deep terrestrial subsurface environments using metaproteogenomics and isotopic analysis.

bioRxiv · Aug 21, 2021Microbiology

Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics and proteomics

P. T. West, S. L. Peters, M. R. Olm, F. B. Yu, Y. C. Lou, B. A. Firek, R. Baker, A. D. Johnson, M. J. Morowitz, R. L. Hettich, J. F. Banfield

This study identifies genetic and behavioral adaptations of C. parapsilosis in the gut microbiome of hospitalized infants using in situ genomics, transcriptomics, and proteomics.

Microbiome · Jun 21, 2021Peer-reviewedMicrobiology

Critical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows

T. Van Den Bossche, B. J. Kunath, K. Schallert, S. S. Schäpe, P. E. Abraham, J. Armengaud, M. O. Arntzen, A. Bassignani, D. Benndorf, S. Fuchs, R. J. Giannone, T. J. Griffin, L. H. Hagen, R. Halder, C. Henry, , Marte

CAMPI evaluates metaproteomic workflows across labs, finding sample processing drives peptide variability while workflows yield similar functional profiles.

bioRxiv · Mar 5, 2021Microbiology

Microbiota functional activity biosensors for characterizing nutrient utilization in vivo

D. A. Wesener, Z. W. Beller, S. L. Peters, A. Rajabi, G. Dimartino, R. J. Giannone, R. L. Hettich, J. I. Gordon

The paper develops MFABs to quantify gut microbiota metabolism of structurally distinct arabinans in vivo using fluorescent beads.

bioRxiv · Nov 2, 2020Microbiology

One-time Nitrogen Fertilization Shifts Switchgrass Soil Microbiomes within a Context of Larger Spatial and Temporal Variation

H. Chen, Z. K. Yang, D. Yip, R. H. Morris, S. J. Lebreux, M. A. Cregger, D. M. Klingeman, D. Hui, R. L. Hettich, S. W. Wilhelm, G. Wang, F. E. Löffler, C. W. Schadt

The paper examines how one-time nitrogen fertilization affects soil microbiomes in switchgrass fields, finding that spatial and temporal variation outweighs fertilization effects.

bioRxiv · Jan 14, 2019Ecology

Comparing DNA, RNA and protein levels for measuring microbial activity in nitrogen-amended soils

L. H. Orellana, J. Hatt, R. Iyer, K. Chourey, R. L. Hettich, J. Spain, W. H. Yang, J. Chee-Sanford, R. A. Sanford, F. E. Löffler, K. T. Konstantinidis

The paper compares DNA, RNA, and protein levels to assess microbial activity in nitrogen-amended soils, finding that RNA best correlates with nitrification activity while DNA and proteins show limited correlation.

bioRxiv · Nov 10, 2018 · PreprintMicrobiology

Quantifying Codon Usage in Signal Peptides: Gene Expression and Amino Acid Usage Explain Apparent Selection for Inefficient Codons

A. L. Cope, R. L. Hettich, M. A. Gilchrist

The paper investigates codon usage in E. coli signal peptides and finds that apparent selection for inefficient codons is explained by amino acid usage and gene expression, not selection.

bioRxiv · Jun 28, 2018Evolutionary Biology

Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profiles

C. T. Brown, W. Xiong, M. R. Olm, B. C. Thomas, R. Baker, B. Firek, M. J. Morowitz, R. L. Hettich, J. F. Banfield

This study examines microbial colonization in premature infants, finding distinct proteomic profiles among related bacterial strains and correlations with NEC development.

bioRxiv · Mar 6, 2018Microbiology