ImmunologybioRxiv
Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses
DOI 10.1016/j.celrep.2022.111311
Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
P. Mendoza, J. R. Jackson, T. Oliveira…·L. B. Cohn
The paper shows that antigen-responsive CD4+ T cell clones with latent HIV-1 proviruses persist in individuals, suggesting antigen exposure contributes to reservoir longevity.
E. Battivelli, M. S. Dahabieh, M. Abdel-Mohsen…·E. Verdin
The paper identifies that latency reversing agents reactivate less than 5% of latent HIV proviruses and shows distinct chromatin functional states between reactivated and non-reactivated cells.