ImmunologybioRxiv
Tumor-Specific CD8+ T Cells from the Bone Marrow Resist Exhaustion and Exhibit Increased Persistence in Tumor-Bearing Hosts as Compared to Tumor Infiltrating Lymphocytes
E. M. Zawidzka, L. Biavati, A. Thomas…·I. Borrello
This study compares tumor-specific CD8+ T cells from the bone marrow with tumor-infiltrating lymphocytes, finding BM T cells to be more effective in persistence and function for adoptive cell therapy.
DOI 10.1136/jitc-2024-009367