Author

L. Breen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Philp· 1 shared B. Nolan· 1 shared C. Craik· 1 shared D. Fennelly· 1 shared D. L. Hamilton· 1 shared E. Ryan· 1 shared F. Caiazza· 1 shared F. O'Neill· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

A. Philp

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2 papers

Recent·Most cited

Protein-carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle

N. Hodson, J. R. Dent, Z. Song, M. O'Leary, T. Nicholson, S. W. Jones, J. Murray, S. Jeromson, D. L. Hamilton, L. Breen, A. Philp

This study shows that protein-carbohydrate ingestion in human skeletal muscle increases Vps34 translocation to the cell periphery and its co-localization with mTOR, without altering Vps34 kinase activity or preventing mTORC1 activation.

bioRxiv · Feb 10, 2020Physiology

KH-type splicing regulatory protein controls colorectal cancer cell growth and modulates the tumor microenvironment

F. Caiazza, K. Oficjalska, M. Tosetto, J. Phelan, S. Noonan, P. Martin, K. Killick, L. Breen, F. O'Neill, B. Nolan, S. Furney, R. Power, D. Fennelly, C. Craik, J. O'Sullivan, , E. Ryan

This study investigates KHSRP's role in colorectal cancer, showing it promotes tumor growth and modulates the tumor microenvironment through mechanisms involving cell proliferation and angiogenesis.

bioRxiv · Jun 12, 2019Cancer Biology