Parallel Molecular Data Storage by Printing Epigenetic Bits on DNA
C. Zhang, R. Wu, F. Sun…·H. Yan
This paper introduces a DNA-based data storage method using epigenetic modifications, achieving scalable and parallel data writing and retrieval.
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54 papers
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C. Zhang, R. Wu, F. Sun…·H. Yan
This paper introduces a DNA-based data storage method using epigenetic modifications, achieving scalable and parallel data writing and retrieval.
D. Wang, Y. Qiang, J. Guo…·J. Han
The paper describes a new Cambrian ecdysozoan species, Beretella spinosa, and suggests that ancestral ecdysozoans may have been non-vermiform.
Y. Niu, Y. Zhang, X. Wang…·L. Li
This study compares phenotypic and transcriptomic features of sun- and shade-grown Araliaceae species under different light conditions, revealing differences in photosynthesis efficiency and gene regulation.
K. Guo, Z. Song, J. Zhou…·H. Wang
This paper introduces an AI-assisted digital microfluidic system called DropAI for multistate droplet control using semantic segmentation and state machine feedback.
Z. Yang, S. Zhou, Q. Zhang…·J. Sun
This study identifies LPHN2/ADGRL2 as a force-sensitive adhesion GPCR essential for normal equilibrioception by regulating mechanoelectrical transduction in utricular hair cells.
z. yang, s. zhou, m. wang…·J. Sun
This study identifies GPR133 as a force-sensing GPCR essential for balance, showing it modulates vestibular hair cell excitability via Gi signaling and CNGA3 coupling.
J. Park, R. Hu, S. Xiong…·Y. Jiang
This study shows estrogen prevents age-related failure in beige adipogenesis by controlling ER stress via NAMPT, improving energy expenditure and glucose tolerance in mice.
Z. Song, Y. Li, Y. Li…·Y.-H. P. J. Zhang
This paper describes an in vitro biotransformation pathway using two decarboxylases to convert -alanine to {beta}-alanine with 100% carbon atom economy by fixing CO2.
Y. Pan, Q. Xue, Y. Yang…·J. Wei
This paper develops a PD-1-iRGD conjugate that enhances antitumor efficacy by improving T cell engagement and penetration, and expands a unique population of CD8+ T cells in the tumor microenvironment.
F. Wang, X. Liu, F. Huang…·W. Wang
This study shows metformin reduces hepatic ischemia/reperfusion injury by altering gut microbiota to increase GABA, which inhibits ferroptosis.
Z. Song, K.-W. Wang, H.-T. C. Hagar…·M.-H. Kuo
This study shows hyperphosphorylated tau causes ER stress and inflammation, which are reduced by apomorphine and HO-1 overexpression.
C. Xiao, Y. Sun, H. Huang…·S. Xu
This paper develops a multiscale model for ion transport in multicellular tissues and applies it to study smooth muscle cell activation under various stimuli, showing the importance of gap junctions and extracellular potassium.
J. Lu, J. Zhang, H. Jiang…·X. Yu
This study identifies Vangl2 as a negative regulator of NF-κB signaling in sepsis by promoting autophagic degradation of p65 through NDP52.
R. Wu, J. Park, Y. Qian…·Y. Jiang
This study shows that Cdkn2a regulates beige fat maintenance via BECN1-mediated autophagy, with implications for obesity and diabetes treatment.
Y. Chen, X. Lin, Z. Song, Y. Liu
The paper analyzes divorce rates in birds using phylogenetic methods and finds male promiscuity and migration distance correlate with higher divorce rates.
H. Li, Z. Gao, Z. Song…·Y. Zhang
The paper demonstrates that swim bladder resonance enhances hearing in crucian carp through auditory evoked potentials, Micro-CT, and numerical simulations.
J. Chang, A. Saraswathibhatla, Z. Song…·O. Chaudhuri
This study shows breast cancer cells invade the basement membrane using both proteases and mechanical forces from cell volume expansion and local contractility.
Y. Ju, Z. Zhang, M. Liu…·R. Guo
This study analyzes the nasal microbiome of healthy young adults, revealing sex-specific differences in composition and ecological stability between males and females.
J. Li, R. Zhang, T. Li…·Y. Liu
This paper develops an ultra-high-throughput method for microbial single-cell whole genome sequencing to study microbial dark matter and improve metagenomic analysis.
C. Dougan, Z. Song, H. Fu…·S. Peyton
This study measures fracture energy in intact brain tissue using needle-induced cavitation and hydraulic fracture models, finding values between 1.5 to 8.9 J/m2 depending on location and model.
Y. Zhang, Y. Niu, X. Wang…·l. Li
This study compares phenotypic and transcriptomic responses of sun- and shade-loving plants to sunlight and dim-light conditions, finding that shade-loving ginseng shows lower phenotypic plasticity but higher photosynthetic efficiency under dim light.
Z. Sun, Y. Wang, Z. Song…·Y. Fang
This study investigates how DNA methylation in transposable elements disrupts the link between 3D chromatin organization and gene expression in rice after genome duplication.
Z. Song, L. Wang, C. C. Lai…·G. Yue
This study investigates how salt stress affects oil palm by analyzing gene expression and stomatal development, finding that EgSPCH promotes stomatal increase which aids in salt tolerance.
H. Ma, Y. Guo, H. Tang…·J. Zhu
This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.
K. Bao, J. Feng, W. Liu…·L. Bao
This study identifies JM03, a crotamiton derivative, as a small molecule that extends C. elegans lifespan and improves stress resistance by inhibiting OSM-9 and activating SKN-1 signaling.
K. M. Beussman, M. Y. Mollica, A. Leonard…·N. J. Sniadecki
This paper introduces a traction force microscopy technique called 'black dots' to measure cellular forces without constraining cell shape, finding that higher force correlates with increased spread area, circularity, and F-actin uniformity in platelets.
M. Wang, B. Li, S. Li…·X. Zhang
This paper reviews selenium content in wheat farming soil, grain, and derived foods globally, showing how agronomic practices can enhance selenium levels in wheat and its products.
S. Yuan, Y. Chen, Y. Song…·G. Sun
This study uses single cell Raman-DIP to rapidly determine antimicrobial susceptibility of Elizabethkingia spp. and confirms minocycline and levofloxacin as first-line treatments.
Y. Zhang, J. Zhang, Y. Chen…·H. Zhang
This study identifies SARS-CoV-2 ORF8 as a protein that downregulates MHC-I to evade immune detection by promoting lysosomal degradation, reducing CTL-mediated cell elimination.