Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy
L. Chambers, E. L. Esakov, C. Braley, L. Trestan, Z. Alali, D. Bayik, J. Lathia, N. Sangwan, P. Bazeley, A. S. Joehlin-Price, M. Dwidar, A. Hajjar, P. P. Ahern, J. Claesen, P. Rose, , O. Reizes
This study shows that antibiotic treatment disrupts the gut microbiome, leading to increased resistance to cisplatin in ovarian cancer models.
bioRxiv · Jun 16, 2020 · PreprintCancer Biology