HMGB1 acts as an agent of host defense at the gut mucosal barrier
A.-M. C. Overstreet, B. Anderson, M. Burge, X. Zhu, Y. Tao, C. Cham, B. Michaud, S. Horam, N. Sangwan, M. Dwidar, X. Liu, A. Santos, C. Finney, Z. Dai, V. Leone, J. S. Messer
This study identifies HMGB1 as a host defense molecule in the gut mucosal barrier that targets bacterial adhesins to prevent microbial invasion and adhesion.
bioRxiv · May 30, 2023 · PreprintMicrobiology