Heterogeneity of Inflammation-associated Synovial Fibroblasts in Rheumatoid Arthritis and Its Drivers
M. H. Smith, V. R. Gao, M. Schizas, A. Kochen, E. DiCarlo, S. Goodman, T. M. Norman, L. Donlin, C. S. Leslie, A. Y. Rudensky
The paper identifies six distinct synovial fibroblast states in RA driven by cytokine exposure and shows similarities to fibroblast states in other tissues.
bioRxiv · Feb 28, 2022Immunology