J. Rangel-Moreno

SPP1hi macrophages in RA synovial fibrin deposits promote tissue hyperplasia.

The paper identifies ALCAM-CD6 co-stimulation as a pathway promoting IgG2b class-switching in lymph nodes during advanced inflammatory arthritis using spatial and single-cell transcriptomics.

This paper introduces bi-reporter vaccinia viruses expressing both fluorescent and luciferase genes to track viral infections in vitro and in vivo, enabling detailed study of infection dynamics and host-pathogen interactions.

This study identifies lung epithelial signaling as critical for early vaccine-induced CD4+ T cell activation and Mtb control in BCG vaccinated hosts.

The paper identifies NR4A-expressing B cells in RA synovium that show activated transcriptomic profiles and somatic hypermutation, suggesting in situ differentiation and roles in ELS and immune responses.

This study shows that Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport, leading to altered immune responses and iBALT formation.