ImmunologybioRxivPreprint
Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression
N. Meednu, J. Rangel-Moreno, F. Zhang…·J. H. Anolik
The paper identifies NR4A-expressing B cells in RA synovium that show activated transcriptomic profiles and somatic hypermutation, suggesting in situ differentiation and roles in ELS and immune responses.