Author

L. E. Farleigh

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Albecka· 1 shared C. H. Douse· 1 shared D. M. Prigozhin· 1 shared I. A. Tchasovnikarova· 1 shared P. J. Lehner· 1 shared R. T. Timms· 1 shared S. M. Freund· 1 shared S. Maslen· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Albecka

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1 paper

Recent·Most cited

BiochemistrybioRxivDec 18, 2019

Periphilin self-association underpins epigenetic silencing by the HUSH complex

D. M. Prigozhin, A. Albecka, C. H. Douse…·Y. Modis

This study identifies the physicochemical properties of Periphilin required for HUSH complex assembly and epigenetic silencing, showing its N-terminal domain drives aggregation and repressive mark deposition.

DOI 10.1093/nar/gkaa785

humanproteomics

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