BioengineeringbioRxiv
Computer-Assisted Engineering of Hyperstable Fibroblast Growth Factor 2
P. Dvorak, D. Bednar, P. Vanacek…·J. Damborsky
This paper describes the engineering of a hyperstable FGF2 variant with nine mutations using a computer-assisted strategy, achieving high stability without losing biological function.
DOI 10.1002/bit.26531