Cancer BiologybioRxivPreprint
Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors
S. Farouk Sait, K.-h. Tang, S. Angus…·L. F. Parada
This study shows that combining SHP2 and autophagy inhibition effectively suppresses NF1-associated MPNSTs in mouse models, suggesting a potential new treatment approach.
DOI 10.1101/2022.08.18.504317