Author

L. Flippe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Guillonneau· 2 shared I. Anegon· 2 shared L. David· 2 shared A. BRUNEAU· 1 shared A. Freuchet· 1 shared A. GAIGNERIE· 1 shared A. Salama· 1 shared B. BRETIN· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

C. Guillonneau

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single cell analysis reveals CD45RClow/-TNFR2+CD29lowCD8+ Tregs with superior activity

C. Serazin, L. Flippe, M. Streitz, D.-J. Wendering, S. Schlickeiser, F. Heinrich, P. Durek, G. M. Guerra, K. Lehmann, M.-F. Mashreghi, H. Wajant, H.-D. Volk, I. Anegon, L. David, S. Bezie, C. Guillonneau

The paper identifies and characterizes three subsets of human CD8+ regulatory T cells using single-cell CITE-seq and VDJ sequencing, highlighting a subset with superior suppressive activity.

bioRxiv · Dec 13, 2023 · PreprintImmunology

IL-34 deficiency impairs FOXP3+ Treg function and increases susceptibility to autoimmunity

A. Freuchet, A. Salama, S. Bézie, L. Tesson, S. Rémy, R. Humeau, H. Règue, L. Flippe, P. Peterson, N. Vimond, C. Usal, S. Ménoret, J.-M. Heslan, F. Duteille, F. Blanchard, , C. Guillonneau

This study shows IL-34 deficiency impairs FOXP3+ Treg function, leading to autoimmunity and increased susceptibility to colitis and graft rejection.

bioRxiv · Feb 4, 2022 · PreprintImmunology

Generation of human induced trophoblast stem cells

G. CASTEL, D. MEISTERMANN, B. BRETIN, J. FIRMIN, J. BLIN, S. LOUBERSAC, A. BRUNEAU, S. CHEVOLLEAU, S. KILENS, C. CHARIAU, A. GAIGNERIE, Q. FRANCHETEAU, H. KAGAWA, E. CHARPENTIER, L. FLIPPE, , L. DAVID

This study generates human induced trophoblast stem cells (hiTSC) from post-natal cells using reprogramming and fate conversion, enabling diverse genetic modeling of placental development and disease.

bioRxiv · Sep 15, 2020Cell Biology