Colon resident CD8+ T cells from people with HIV on antiretroviral therapy exhibit mitochondrial dysfunction and impaired responses
U. Das Adhikari, P. V. Shah, L. M. Froehle, A. H. Linder, M. Flagg, C. Crawlings, M. R. Junca, L. Folarin, F. Karim, J. Z. Li, H. Kloverpris, D. S. Kwon
The paper examines CD8+ T cells in the colon of HIV patients on ART, finding impaired mitochondrial function and reduced immune responses compared to peripheral blood cells.
bioRxiv · May 2, 2023 · PreprintImmunology