Author

M. Flagg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Assay:metabolomics· 2 Assay:proteomics· 2

Frequent Co-Authors

E. de Wit· 3 shared N. van Doremalen· 3 shared V. Munster· 3 shared A. Okumura· 2 shared B. Smith· 2 shared B. Williamson· 2 shared F. Feldmann· 2 shared J. E. Schulz· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

E. de Wit

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

A. Wickenhagen, M. Flagg, J. Port, C. K. Yinda, K. Goldin, S. Gallogly, J. E. Schulz, T. Lutterman, B. Williamson, F. Kaiser, R. Mukesh, S. Van Tol, B. Smith, N. van Doremalen, C. Russell, , V. Munster

This study evaluates the fitness and pathogenesis of Omicron variants in the upper and lower respiratory tracts, finding increased URT fitness with reduced lung pathology.

bioRxiv · Jun 13, 2024Microbiology

Colon resident CD8+ T cells from people with HIV on antiretroviral therapy exhibit mitochondrial dysfunction and impaired responses

U. Das Adhikari, P. V. Shah, L. M. Froehle, A. H. Linder, M. Flagg, C. Crawlings, M. R. Junca, L. Folarin, F. Karim, J. Z. Li, H. Kloverpris, D. S. Kwon

The paper examines CD8+ T cells in the colon of HIV patients on ART, finding impaired mitochondrial function and reduced immune responses compared to peripheral blood cells.

bioRxiv · May 2, 2023 · PreprintImmunology

Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques

E. Speranza, J. N. Purushotham, J. R. Port, B. Schwarz, M. Flagg, B. N. Williamson, F. Feldmann, M. Singh, L. Perez-Perez, G. L. Sturdevant, L. M. Roberts, A. Carmody, J. E. Schulz, N. van Doremalen, A. Okumura, , E. de Wit

This study compares immune dynamics in young and old rhesus macaques infected with SARS-CoV-2, finding age-related differences in post-acute immune responses but similar acute disease outcomes.

bioRxiv · Sep 8, 2021Immunology

Subtle differences in the pathogenicity of SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in rhesus macaques

V. Munster, M. Flagg, M. Singh, B. Williamson, F. Feldmann, L. Perez-Perez, B. Brumbaugh, M. Holbrook, D. Adney, A. Okumura, P. Hanley, B. Smith, J. Lovaglio, S. Anzick, C. Martens, , E. de Wit

This study compares the pathogenicity of SARS-CoV-2 variants B.1.1.7 and B.1.351 in rhesus macaques, finding differences in clinical outcomes and immune responses.

bioRxiv · May 7, 2021Microbiology