Author

L. G. Rahme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

V. K. SINGH· 2 shared A. A. Tzika· 1 shared A. Bandyopadhaya· 1 shared A. Chakraborty· 1 shared A. Felici· 1 shared C. Pignaffo· 1 shared D. Andreotti· 1 shared D. Maura· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

V. K. SINGH

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Author profile →

2 papers

Recent·Most cited

MicrobiologybioRxivApr 27, 2022

Tackling Recalcitrant Pseudomonas aeruginosa Infections In Critical Illness via Anti-virulence Monotherapy

V. K. SINGH, M. Almpani, D. Maura…·L. G. Rahme

This study identifies novel anti-MvfR compounds (NAMs) that reduce intestinal permeability and inflammation in Pseudomonas aeruginosa infections, offering a potential monotherapy for critical illness.

DOI 10.1038/s41467-022-32833-9

mouseexperimental assay

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MicrobiologybioRxivPreprintOct 3, 2021

Immunometabolic hijacking of immune cells by a Pseudomonas aeruginosa quorum-sensing signal

A. Bandyopadhaya, V. K. Singh, A. Chakraborty…·L. G. Rahme

This study shows how Pseudomonas aeruginosa uses a quorum-sensing signal to reprogram macrophage metabolism, reducing energy and immune responses to promote pathogen persistence.

DOI 10.1101/2021.10.03.462785

mousemetabolomics

𝕏 PostBluesky