Author

L. Herring

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Mills· 1 shared A. Mordant· 1 shared A.-M. Turner· 1 shared B. Rushing· 1 shared C. Vaziri· 1 shared D. Margolis· 1 shared D. Wu· 1 shared F. Potjewyd· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Mills

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2 papers

Recent·Most cited

MAPK14/p38α Shapes the Molecular Landscape of Endometrial Cancer and promotes Tumorigenic Characteristics

S. Joseph, X. Zhang, G. Droby, D. Wu, V. Bae-Jump, S. Lyons, A. Mordant, A. Mills, L. Herring, B. Rushing, J. Bowser, C. Vaziri

This study identifies MAPK14/p38α as critical for HGEC spheroid growth, shaping its transcriptomic, proteomic, and metabolomic landscapes and promoting tumorigenic properties.

bioRxiv · Jun 25, 2024Cancer Biology

Degradation of Polycomb Repressive Complex 2 with an EED-targeted Bivalent Chemical Degrader

F. Potjewyd, A.-M. Turner, J. Beri, J. Rectenwald, J. Norris-Drouin, S. Cholensky, D. Margolis, K. Pearce, L. Herring, L. I. James

This paper introduces a bivalent chemical degrader, UNC6852, that targets PRC2 components and demonstrates its ability to degrade PRC2 and inhibit EZH2 activity in cancer cells.

bioRxiv · Jun 21, 2019Cancer Biology