Cancer BiologyCancersPeer-reviewed
Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy
E. Gomez-Castaneda, S. Rogers, C. Munje…·T. Holyoake
The paper identifies TKI-independent genes in CML LSC that could be targeted for new therapies, showing that gemtuzumab-ozogamicin and cyclosporine A have stronger effects on CML cells than healthy cells.
DOI 10.3390/cancers14215253