Cell BiologyeLifePeer-reviewed
MicroRNA-deficient embryonic stem cells acquire a functional Interferon response
J. Witteveldt, L. I. Knol, S. Macias
The paper shows that miRNA-deficient ESCs develop a functional IFN response, with miR-673 regulating MAVS to suppress antiviral IFN during pluripotency.
DOI 10.7554/elife.44171