L. Lopez

Investigating Novel Streptomyces Bacteriophage Endolysins as Potential Antimicrobial Agents

The paper identifies three Streptomyces phage endolysins with PG-degrading activity and antimicrobial potential against ESKAPE bacteria, with LL35lys showing low MIC against Gram-positive strains.

DCs targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors

The paper shows that DC-based therapy enhances CD8 T cell responses to neoantigens in lung tumors, particularly in high TMB tumors.

Century-long timelines of herbarium genomes predict plant stomatal response to climate change

The paper uses historical A. thaliana genomes and genetic knowledge to show a decrease in stomatal density over time linked to climate change.

The genomics and physiology of abiotic stressors associated with global elevation gradients in Arabidopsis thaliana

This study investigates elevational adaptation in Arabidopsis thaliana by analyzing genetic and physiological responses to abiotic stressors across different regions.

Systematic review of Plasmodium falciparum and Plasmodium vivax polyclonal infections: Impact of prevalence, study population characteristics, and laboratory procedures

This study reviews polyclonal infections of Plasmodium falciparum and P. vivax, finding that prevalence correlates with polyclonality but the relationship is weak.

In the presence of population structure: From genomics to candidate genes underlying local adaptation

The paper compares mixed linear models and Spearman correlations for identifying SNPs associated with climate, finding that SNPs from both methods are enriched for local adaptation but only GEMMA-associated SNPs show functional constraint and fitness QTL linkage.

Evolutionary changes of an intestinal Lactobacillus reuteri during probiotic manufacture

This study shows that repeated growth of Lactobacillus reuteri in milk reduces its ability to grow in culture media and possibly colonize the mammalian intestine.