DCs targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
L. Lopez, L. G. Morosi, F. La Terza, P. Bourdely, G. Rospo, R. Amadio, G. M. Piperno, V. Russo, C. Volponi, S. Vodret, S. Joshi, F. Giannese, D. Lazarevic, G. Germano, P. Stoitzner, , F. Benvenuti
The paper shows that DC-based therapy enhances CD8 T cell responses to neoantigens in lung tumors, particularly in high TMB tumors.
bioRxiv · Jan 26, 2024 · PreprintImmunology