Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient
C. A. Colque, P. E. Tomatis, A. G. Albarracin Orio…·A. M. Smania
This study tracks the long-term evolution of antibiotic-resistant Pseudomonas aeruginosa in a cystic fibrosis patient, revealing diverse genetic changes that enhance resistance to multiple cephalosporins.