Author

L. Macdonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

B. Dupuy· 2 shared B. Iannascoli· 2 shared C. Guo· 2 shared D. Sterlin· 2 shared G. Gorochov· 2 shared L. Hunault· 2 shared M. Kurowska-Stolarska· 2 shared P. Bruhns· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

B. Dupuy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A monoclonal antibody collection for C. difficile typing

L. Hunault, P. England, F. Barbut, B. Iannascoli, O. Godon, F. Dejardin, C. Thomas, B. Dupuy, C. Guo, L. Macdonald, G. Gorochov, D. Sterlin, P. Bruhns

The paper develops a monoclonal antibody collection targeting C. difficile strains to improve research on clinically relevant ribotypes.

bioRxiv · Sep 21, 2023 · PreprintImmunology

Anti-S-layer monoclonal antibodies impact Clostridioides difficile physiology

L. Hunault, E. Auria, P. England, J. Deschamps, R. Briandet, V. Kremer, B. Iannascoli, L. Vidal-Maison, C. Guo, L. Macdonald, S. Pechine, C. Deneve-Larrazet, B. Dupuy, G. Gorochov, P. Bruhns, D. Sterlin

This study identifies monoclonal antibodies targeting C. difficile's S-layer protein, revealing both protective and detrimental effects on bacterial physiology.

bioRxiv · Sep 21, 2023 · PreprintMicrobiology

Primed to resolve: A single cell atlas of the shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis

M. T. Ng, R. Borst, H. Gacaferi, S. Davidson, C. C. Machado, I. Reekie, M. Attar, D. Windell, M. Kurowska-Stolarska, L. MacDonald, S. Alivernini, M. Garvilles, K. Jansen, A. Bhalla, A. Lee, , S. G. Dakin

This study identifies MERTK+ macrophages and fibroblasts involved in resolving fibrosis in frozen shoulder using single-cell analysis and suggests therapeutic strategies to enhance their interaction.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

COVID-19 and Rheumatoid Arthritis share myeloid pathogenic and resolving pathways

L. MacDonald, T. D. Otto, A. Elmesmari, B. Tolusso, D. Somma, C. McSharry, E. Gremese, I. B. McInnes, S. Alivernini, M. Kurowska-Stolarska

This study identifies shared myeloid pathways between COVID-19 pneumonitis and RA synovitis, highlighting MerTK as a therapeutic target for both conditions.

bioRxiv · Jul 26, 2020 · PreprintImmunology