Author

L. Mannion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Russell· 1 shared A. Smith· 1 shared D. J. Winton· 1 shared F. Perrone· 1 shared K. Nayak· 1 shared M. Zilbauer· 1 shared N. Skoufou-Papoutsaki· 1 shared P. D'Santos· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Russell

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1 paper

Recent·Most cited

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR

N. Skoufou-Papoutsaki, S. Adler, P. D'Santos, L. Mannion, S. Mehmed, R. Kemp, A. Smith, F. Perrone, K. Nayak, A. Russell, M. Zilbauer, D. J. Winton

This study develops an efficient ribonucleoprotein-based CRISPR method for editing human intestinal organoids, achieving 98% editing efficiency with no off-target effects and revealing PTEN loss phenotypes.

bioRxiv · Mar 31, 2023 · PreprintCell Biology