Author

L. Mesch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Achberger· 3 shared M. Cipriano· 3 shared P. Loskill· 3 shared S. Liebau· 3 shared A. Kleger· 2 shared M. Mesquida· 2 shared N. Pashkovskaia· 2 shared S. Corti· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioengineering

K. Achberger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aged human iPSC-RPE organoid cultures display hallmarks of drusen formation

L. Mesch, N. Pashkovskaia, V. Cora, S. Pars, S. Corti, M. Cipriano, P. Loskill, E. Koertvely, S. Kustermann, M. Mesquida, A. Kleger, S. Liebau, K. Achberger

This study develops an in vitro model of aged human iPSC-derived RPE organoids that display AMD-like features including drusen formation and age-related alterations.

bioRxiv · Oct 12, 2021 · PreprintCell Biology

Human immunocompetent Choroid-on-Chip: a novel tool for studying ocular effects of biological drugs

M. Cipriano, K. Schluender, C. Probst, K. Linke, M. Weiss, M. J. Fischer, L. Mesch, K. Achberger, S. Liebau, M. Mesquida, V. Nicolini, A. Schneider, A. M. Giusti, S. Kustermann, P. Loskill

The paper develops a human immunocompetent Choroid-on-Chip model to study ocular effects of biological drugs and assess immunotoxicity.

bioRxiv · May 12, 2021Bioengineering

Human stem cell-based retina-on-chip as new translational model for validation of AAV retinal gene therapy vectors

K. Achberger, M. Cipriano, M. Duechs, C. Schoen, S. Michelfelder, B. Stierstorfer, T. Lamla, S. Kauschke, J. Chuchuy, J. Roosz, L. Mesch, V. Cora, S. Pars, N. Pashkovskaia, S. Corti, , P. Loskill

The paper evaluates seven AAV vectors using a human stem cell-derived Retina-on-chip model to assess their efficacy, kinetics, and cell tropism.

bioRxiv · Mar 2, 2021Bioengineering