M. Weiss

Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis

This study shows that neutrophil extracellular traps (NETs) drive tumor necrosis and metastasis in colorectal cancer, and inhibiting NET formation reduces necrosis and improves chemotherapy outcomes.

Insectivorous birds and bats outperform ants in the top-down regulation of arthropods across strata of a Japanese temperate forest

This study compares the top-down control effects of birds, bats, and ants on arthropod communities and plant damage across forest strata in a Japanese temperate forest.

Intermittent subdiffusion of short nuclear actin rods due to interactions with chromatin

The paper uses single-particle tracking to study the transport of nuclear actin rods and finds intermittent subdiffusion due to interactions with chromatin.

Deletion of SMC renders FtsK essential in Corynebacterium glutamicum

This paper shows that in Corynebacterium glutamicum, deletion of SMC makes FtsK essential for chromosome segregation, as FtsK compensates for SMC loss by extending its activity at the septum.

Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens

The paper identifies auto-antibodies secreted by plasma cells in PDAC against self-antigens, suggesting a link between chronic inflammation and autoimmunity.

Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency

The paper develops MATAC-Seq to analyze single-molecule chromatin accessibility at replication origins, identifying chromatin features that predict origin efficiency in yeast.

The CGG triplet repeat binding protein 1 counteracts DNA secondary structure-induced transcription-replication conflicts

This study shows CGGBP1 binds to short trinucleotide repeats to prevent transcription-replication conflicts caused by secondary DNA structures.

ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics

ResFinderFG v2.0 is a database of antibiotic resistance genes from functional metagenomics, improving resistome description by detecting ARGs not found in conventional databases.

A novel nuclease is the executing part of a bacterial plasmid defense system

The paper identifies MksG as a novel nuclease in the MksBEFG plasmid defense system of Corynebacterium glutamicum, showing it degrades plasmid DNA and is regulated by DivIVA.

SegVeg: Segmenting RGB images into green and senescent vegetation by combining deep and shallow methods

SegVeg segments RGB images into green and senescent vegetation using a hybrid deep and shallow learning approach, achieving high accuracy for green vegetation but lower for senescent and background.

Probing local chromatin dynamics by tracking telomeres

This study tracks telomere movement in interphase cells to investigate local chromatin dynamics, revealing subdiffusive motion and niche visits under physiological conditions.

Generic principles of space compartmentalization in protocell patterns

This study shows that protocell patterns exhibit organized spatial arrangements similar to epithelial monolayers, emerging from simultaneous seed formation and coarsening without genetic material.

Deformation-induced actuation of cells in asymmetric periodic flow fields

The paper demonstrates that soft cells can be segregated based on their mechanical properties in asymmetric periodic flow fields, while rigid beads show no net drift.

Autologous human immunocompetent white adipose tissue-on-chip

This paper introduces a human-based, immunocompetent WAT-on-chip model that recapitulates adipose tissue heterogeneity and functions for metabolic research and personalized medicine.

Fresh insights into Mediterranean biodiversity: Environmental DNA reveals spatio-temporal patterns of stream invertebrate communities on Sicily

The paper uses eDNA metabarcoding to study stream invertebrate biodiversity in Sicily, finding seasonal diversity changes and a dispersal barrier.

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

Human immunocompetent Choroid-on-Chip: a novel tool for studying ocular effects of biological drugs

The paper develops a human immunocompetent Choroid-on-Chip model to study ocular effects of biological drugs and assess immunotoxicity.

The Serine Protease HtrA2 mediates radiation-induced senescence in cancer cells

This study identifies HtrA2 as a mediator of radiation-induced senescence in cancer cells, showing its role in proliferation arrest and vimentin filament reorganization.

Individual small in-stream barriers contribute little to strong local population genetic structure five strictly aquatic macroinvertebrate taxa

The paper assesses the impact of small in-stream barriers on genetic structure of five aquatic macroinvertebrates, finding significant effects only for specific barriers and species.

Sublethal concentrations of clothianidin affect honey bee colony behavior and interact with landscapes to affect colony growth

This study shows sublethal clothianidin exposure affects honey bee colony behavior in stressful environments but not in more favorable ones, with CO2 levels indicating stress effects.

Effects of exposure to sublethal concentrations of methoxyfenozide on honey bee colony activity and thermoregulation

This study examines the effects of sublethal methoxyfenozide exposure on honey bee colony activity and thermoregulation, finding significant behavioral changes at higher concentrations.

Diffusion of exit sites on the endoplasmic reticulum - a random walk on a shivering backbone

This study shows that ER exit sites (ERES) exhibit microtubule-dependent anomalous diffusion on ER tubules, distinct from ER junctions, and are not actively moved by microtubules.