Author

S. Pars

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Kleger· 2 shared K. Achberger· 2 shared L. Mesch· 2 shared M. Cipriano· 2 shared N. Pashkovskaia· 2 shared P. Loskill· 2 shared S. Corti· 2 shared S. Liebau· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. Kleger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

S. H. Saber, M. R. Shaker, J. Sng, N. Yak, S. D. Morrison, S. Pars, H. Zheng, G. Pietrogrande, T. Binder, S. Lu, M. Floetenmeyer, R. Ojha, T. Quirin, J. Ruuska, T. Smura, , M. Joensuu

This study shows that inhibiting host N-myristoylation reduces SARS-CoV-2 infectivity by impairing viral envelope protein maturation and causing Golgi-bypassing egress.

bioRxiv · Mar 3, 2023 · PreprintMicrobiology

Aged human iPSC-RPE organoid cultures display hallmarks of drusen formation

L. Mesch, N. Pashkovskaia, V. Cora, S. Pars, S. Corti, M. Cipriano, P. Loskill, E. Koertvely, S. Kustermann, M. Mesquida, A. Kleger, S. Liebau, K. Achberger

This study develops an in vitro model of aged human iPSC-derived RPE organoids that display AMD-like features including drusen formation and age-related alterations.

bioRxiv · Oct 12, 2021 · PreprintCell Biology

Human stem cell-based retina-on-chip as new translational model for validation of AAV retinal gene therapy vectors

K. Achberger, M. Cipriano, M. Duechs, C. Schoen, S. Michelfelder, B. Stierstorfer, T. Lamla, S. Kauschke, J. Chuchuy, J. Roosz, L. Mesch, V. Cora, S. Pars, N. Pashkovskaia, S. Corti, , P. Loskill

The paper evaluates seven AAV vectors using a human stem cell-derived Retina-on-chip model to assess their efficacy, kinetics, and cell tropism.

bioRxiv · Mar 2, 2021Bioengineering