BiochemistrybioRxiv
Inhibition of the proton-activated chloride channel PAC by PIP2
L. Mihaljevic, R. Zheng, J. Osei-Owusu…·Z. Qiu
This study identifies PIP2 as an inhibitor of the PAC channel, revealing its binding site and mechanism through structural and electrophysiological analyses.
DOI 10.7554/elife.83935