A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice.
P. M. Nolan, G. Banks, N. Bourbia, A. G. Wilcox, L. Bentley, L. Moir, L. Kent, R. Hillier, D. Wilson, P. Barrett, R. Dumbell
This study shows that a ZFHX3 mutation in mice reduces body weight, alters metabolism, and changes hypothalamic gene expression related to growth and energy balance.
bioRxiv · May 25, 2022Physiology